Tuesday, May 7, 2013

Profile: Venezuelan President Nicolas Maduro

Position: President of Venezuela

Incumbent: Nicolas Maduro

Date of Birth: November 23, 1962

Term: He became acting president on March 8, 2013, three days after the death of President Hugo Chavez from cancer. Maduro, the ruling Socialist Party's candidate, won the resulting April 14 presidential election and was sworn in five days later.

Key Facts:

- Maduro served six years as foreign minister before being named vice president in October 2012 and then Chavez's handpicked successor two months later. As Chavez's illness worsened, the burly, mustachioed Maduro became the South American nation's de facto leader.

- A former bus driver and union leader and self-declared "Chavista," Maduro is expected to continue Chavez's policies, including nationalizations, tight state control of the economy and financial support for allies such as communist-led Cuba.

- Maduro faced opposition leader Henrique Capriles, the centrist governor of Miranda state, in the April 14 vote. Maduro only narrowly won and Capriles refused to recognize the election result. He has alleged that there were thousands of voting irregularities.

- Like Chavez, Maduro has a penchant for extreme rhetoric. He has accused foes of plotting to assassinate him and suggested that "imperialist" enemies infected Chavez with cancer. In a March 13 speech, Maduro said that "far right" figures in the United States were plotting to kill Capriles.

- Maduro inherited an economy beset by high inflation and unemployment but buoyed by the OPEC member's oil reserves. He has said that private sector hoarding and "speculative attacks" on the bolivar currency were to blame for the economic problems.

- As foreign minister, Maduro had a relatively dull image and never diverted from Chavez's line. He traveled widely, denouncing U.S. foreign policy and cultivating allies in emerging markets such as Russia and China, which would become a key financier.

- In 1992, when Chavez was jailed for a failed coup that made him famous, Maduro took to the streets to demand his release and visited him in prison. Maduro was first elected to the National Assembly in 2000, later becoming its president.

- He was born in Caracas and attended high school in a working-class neighborhood on the outskirts of the city. He began his political career as a trade unionist representing the workers of the Caracas Metro system.

- He is married to Cilia Flores, a former leader of the National Assembly who now serves as the nation's attorney general, and the two have long been viewed as a "power couple" in the government. Maduro was raised a Roman Catholic, and he and his wife are supporters of the late Indian spiritual guru Sai Baba.

(Compiled by Caracas bureau and Washington MPG Desk; Editing by David Cutler and Paul Simao)

Source: http://news.yahoo.com/profile-venezuelan-president-nicolas-maduro-194411818.html

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Monday, May 6, 2013

Genome sequencing provides unprecedented insight into causes of pneumococcal disease

May 5, 2013 ? A new study led by researchers from Harvard School of Public Health (HSPH) and the Wellcome Trust Sanger Institute in the UK has, for the first time, used genome sequencing technology to track the changes in a bacterial population following the introduction of a vaccine. The study follows how the population of pneumococcal bacteria changed following the introduction of the 'Prevnar' conjugate polysaccharide vaccine, which substantially reduced rates of pneumococcal disease across the U.S. The work demonstrates that the technology could be used in the future to monitor the effectiveness of vaccination or antibiotic use against different species of bacterial pathogens, and for characterizing new and emerging threats.

The study appears online May 5, 2013 in Nature Genetics.

"This gives an unprecedented insight into the bacteria living and transmitting among us," said co-author William Hanage, associate professor of epidemiology at HSPH. "We can characterize these bugs to an almost unimaginable degree of detail, and in so doing understand better what helps them survive even in the presence of an effective vaccine."

Pneumococcal disease is caused by a type of bacteria called Streptococcus pneumoniae, which is present in many people's noses and throats and is spread by coughing, sneezing, or other contact with respiratory secretions. The circumstances that cause it to become pathogenic are not fully understood. Rates of pneumococcal disease -- an infection that can lead to pneumonia, meningitis, and other illnesses -- dropped in young children following the introduction of a vaccine in 2000. However, strains of the bacteria that are not targeted by the vaccine rapidly increased and drug resistance appears to be on the rise.

The research, led by HSPH co-senior authors Hanage; Marc Lipsitch, professor of epidemiology; and Stephen Bentley, senior scientist at the Wellcome Trust Sanger Institute, aimed to better understand the bacterial population's response to vaccination. Whole genome sequencing -- which reveals the DNA code for each bacterial strain to an unprecedented level of detail -- was used to study a sample of 616 pneumococci collected in Massachusetts communities from 2001 to 2007.

This study confirmed that the parts of the bacterial population targeted by the vaccine have almost disappeared, and, surprisingly, revealed that they have been replaced by pre-existing rare types of bacteria. The genetic composition of the new population is very similar to the original one, except for a few genes that were directly affected by the vaccine. This small genetic alteration appears to be responsible for the large reduction in the rates of pneumococcal disease.

"The widespread use of whole genome sequencing will allow better surveillance of bacterial populations -- even those that are genetically diverse -- and improve understanding of their evolution," said Lipsitch. "In this study, we were even able to see how quickly these bacteria transmit between different regions within Massachusetts and identify genes associated with bacteria in children of different ages."

"In the future, we will be able to monitor evolutionary changes in real-time. If we can more quickly and precisely trace the emergence of disease-causing bacteria, we may be able to better target interventions to limit the burden of disease," said Bentley.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/7IySghV-p38/130505145928.htm

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Calm, moist air aids fight against Calif. wildfire

Firefighters from Riverside, Calif. work to extinguish a brush fire at Point Mugu, Calif., Friday, May 3, 2013. A Southern California wildfire carving a path to the sea grew to more than 15 square miles and crews prepared Friday for another bad day of gusting winds and searing weather. (AP Photo/Nick Ut)

Firefighters from Riverside, Calif. work to extinguish a brush fire at Point Mugu, Calif., Friday, May 3, 2013. A Southern California wildfire carving a path to the sea grew to more than 15 square miles and crews prepared Friday for another bad day of gusting winds and searing weather. (AP Photo/Nick Ut)

A firefighter keeps watch as the wildfire burns along a hillside in Point Mugu , Calif. Friday, May 3, 2013. Firefighters got a break as gusty winds turned into breezes, but temperatures remained high and humidity levels are expected to soar as cool air moved in from the ocean and the Santa Ana winds retreated. (AP Photo/Ringo H.W. Chiu)

Fire trucks keep an eye on a burned structure at the Naval Base Ventura County (NBVC) at Point Mugu, Calif., Friday, May 3, 2013. The 15 1/2-square-mile blaze was only 10 percent contained on Friday, and the work of more than 900 firefighters, aided by air tankers, was just beginning. (AP Photo/Nick Ut)

A firefighter carries tools down a burned hill after a wildfire in Point Mugu on Friday, May 3, 2013. A huge wildfire carved a path to the sea and burned on the beach Friday, but firefighters got a break as gusty winds turned into breezes. Temperatures remained high, but humidity levels were expected to soar as cool air moved in from the ocean and the Santa Ana winds retreated. (AP Photo/Nick Ut)

A resident waters the burned area next to his home in Point Mugu, Calif., Friday, May 3, 2013. A huge wildfire carved a path to the sea and burned on the beach Friday, but firefighters got a break as gusty winds turned into breezes. Temperatures remained high, but humidity levels were expected to soar as cool air moved in from the ocean and the Santa Ana winds retreated. (AP Photo/Nick Ut)

(AP) ? Moist, cool and calm weather is greatly helping Southern California firefighters battling a huge wildfire in coastal Ventura County.

Fire spokesman Tom Kruschke (KRUSH-kee) says containment of the blaze 50 miles west of Los Angeles has increased to 30 percent Saturday morning.

High winds and dry heat have been replaced by moist air from the ocean, and Kruschke says the fire is significantly laying down. The rugged Santa Monica Mountains are swathed in smoke but flames are no longer prominent.

The fire has burned more than 43 square miles since breaking out near Camarillo (kam-uh-REE-oh) Thursday morning. Flames have threatened thousands of homes since then but only 15 have been damaged.

Weather forecasters say there's a 20 percent chance of rain showers in the area by Sunday afternoon.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-05-04-California%20Wildfires/id-6017579fd1574a2a9e3a05205814fdcf

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Sunday, May 5, 2013

Obama: US-Mexico stereotypes must be broken

US President Barack Obama greets guests before speaking at the Anthropology Museum in Mexico City, Friday, May 3, 2013. (AP Photo/Pablo Martinez Monsivais)

US President Barack Obama greets guests before speaking at the Anthropology Museum in Mexico City, Friday, May 3, 2013. (AP Photo/Pablo Martinez Monsivais)

President Barack Obama and Mexico's President Enrique Pena Nieto, right, leave after offering a joint news conference in Mexico City, Mexico, Thursday, May 2, 2013. Seeking to put a new spin on a long-standing partnership, Obama is promoting jobs and trade - not drug wars or border security - as the driving force behind the U.S.-Mexico relationship. (AP Photo/Dario Lopez-Mills)

A woman holds her child as she attends a protest outside the U.S. embassy before the arrival of President Barack Obama in Mexico City, Thursday, May 2, 2013. (AP Photo/Marco Ugarte)

President Barack Obama answers questions during the news conference with Mexico?s President Enrique Pena Nieto, at the Palacio Nacional in Mexico City, Thursday, May 2, 2013. (AP Photo/Pablo Martinez Monsivais)

MEXICO CITY (AP) ? Calling for an end to "old stereotypes," President Barack Obama on Friday portrayed Mexico as an emerging nation that is remaking itself and said the U.S.-Mexico relationship should be defined by shared prosperity, not by threats that both countries face. "It's time to recognize new realities," he declared.

In a speech to a predominantly student audience, Obama conceded that the root of much violence in Mexico is the demand for drugs in the United States, and acknowledged that most guns used to commit crime in this country come from the U.S. But he said an improving economy is changing Mexico and improving its middle class.

"I see a Mexico that is deepening your democracy," he told several hundred people gathered on a cool, breezy morning in a covered, outdoor plaza at Mexico City's grand National Museum of Anthropology. "Citizens who are standing up and saying that violence and impunity is not acceptable."

Obama said he is optimistic that the U.S. will change its patchwork of immigration laws and says the current immigration system does not reflect U.S. values. With about 6 million Mexicans illegally in the United States, the issue resonates deeply in Mexico, which has also seen deportations of its citizens from the U.S. rise dramatically under Obama.

Underlying Obama's visit was his desire to convince the American public and U.S. lawmakers that Mexico no longer poses the illegal immigration threat it once did.

"The long-term solution to the challenge of illegal immigration is a growing, prosperous Mexico that creates more jobs and opportunity right here," he said.

To that end, he called for improving an already growing trade relationship between the two countries. Mexico is the second-largest export market for U.S. goods and services and the U.S. buys more Mexican exports than any other country.

Still, the reality of Mexico's economic surge is perhaps not as rosy as Obama portrayed it. While the Mexican economy has grown, it has yet to trickle down to average workers.

Obama spoke on the second day of his Mexico City visit, before traveling to Costa Rica. There, he planned to deliver a blunter message to Central American leaders struggling with weak economies and drug violence.

Obama was to meet with Costa Rican President Laura Chinchilla before joining leaders from the Central American Integration system. The regional network also includes the leaders of Belize, El Salvador, Guatemala, Honduras, Nicaragua and Panama.

The U.S. view of the region is that its pervasive violence and security weaknesses are holding back economic growth, and that with fewer Mexicans crossing the border illegally, the rest of the region has become the main source of illegal immigration into the United States.

As a result, Obama is expected to call for stepped up security cooperation, regional economic integration and improvements in human rights and democratic reforms.

"We want to make sure that our hemisphere is more effectively integrated to improve the economy and security of all peoples," Obama said Thursday. "There is a whole range of opportunities, and that will be the purpose of this trip."

Friday's speech came as Obama's popularity in Mexico has risen in recent years and as views of the United States also improve. A Pew Research Center poll in March found that two-thirds of Mexicans have a favorable opinion of the U.S., compared with 44 percent in 2010. About half of Mexicans have confidence that Obama will do the right thing on world affairs, up from 38 percent in 2011.

Still, dozens of migrant families deported from the U.S. even though their children were born there rallied outside the U.S. Embassy before Obama's arrival Thursday. "Obama, don't deport my Mama," one sign said. So far, the Obama administration has deported more than 1.6 million people.

For all the attention to commerce and trade, the visit to Mexico ? less than two days long ? was not designed for major breakthroughs or new initiatives. Indeed, on one of the top economic pacts before them, the two presidents merely reaffirmed a goal to conclude negotiations this year on a Trans-Pacific Partnership, an Asia-Pacific trading bloc that is key to Obama's efforts to boost exports to Asia.

Both men, however, did announce a new partnership to build on the business relationship with closer cooperation between top officials in Mexico and the U.S., including Vice President Joe Biden.

At a joint news conference Thursday, Obama and Pena Nieto carefully sidestepped potential trouble spots. Obama steered clear of commenting on Pena Nieto's decision to end the broad access that U.S. security agencies have had in Mexico to combat drug trafficking, a decision that has alarmed some U.S. officials.

"President Pena Nieto and his team are organizing a vision about how they can most efficiently and effectively address these issues," Obama said. "And we will interact with them in ways that are appropriate, respecting that ultimately Mexico has to deal with its problems internally and we have to deal with ours as well."

For his part, Pena Nieto declined to get drawn into the current immigration debate in Washington, a top priority for Obama but one that is at a delicate stage in Congress. Asked to comment on the debate, the Mexican president merely said the Mexican government acknowledged the efforts under way in Congress.

"Mexico understands that this is a domestic affair for the U.S. and we wish you the best push that you're giving to immigration," he said.

Likewise, he demurred when asked to react to the failure in the U.S. Senate to pass gun control legislation, including an expanded background check for firearms buyers, even though many guns obtained illegally in the U.S. make their way into the hands of drug dealers in Mexico.

He said he agreed with Obama's campaign to stem gun violence, but added: "This is a domestic issue in the United States."

Obama vowed to keep pressing for gun legislation, saying: "We recognize we've got obligations when it comes to guns that are oftentimes being shipped down South and contributing to violence here in Mexico."

___

Follow Jim Kuhnhenn on Twitter: http://twitter.com/jkuhnhenn

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-05-03-LT-Obama/id-e229a944a96e4f0aa849b691a346e408

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California wildfire: 1,900 on the lines as firefighters labor to limit damage (+video)

Saturday's more favorable weather and the heroic work of 1,900 firefighters have limited damage from a fast-breaking California wildfire in Ventura County. State outlook is for an active fire season; elsewhere in the US conditions are less ominous.

By Patrik Jonsson,?Staff writer / May 4, 2013

Hand crews work on the fire line after a wildfire near Point Mugu, Calif., Saturday. On Saturday, high winds and withering hot, dry air were replaced by the normal flow of damp air off the Pacific, significantly reducing fire activity.

Ringo H.W. Chiu/AP

Enlarge

After the monstrous Springs Fire in California's Ventura County tripled in size Friday, firefighters battled the blaze to 30 percent containment on Saturday, helped by the approach of cooler, wetter conditions battening down the flames.

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The fire threatened some 4,000 homes as it consumed 43 squares miles on the western slope of the Santa Monica Mountains, at one point with flames racing all the way to the Pacific Coast Highway. No deaths or injuries have been reported. Some 15 homes have been slightly damaged, but improving weather conditions, the yeoman work of some 1,900 firefighters, and fire-dampening preparations by homeowners have limited more widespread damage so far.

The National Weather Service predicted cooler temperatures, more settled winds, higher humidity, and a 20 percent chance of rain going into Sunday, which should continue to help firefighters lay breaks and contain larger portions of the blaze.

?The fire is really laying down,? said Tom Kruschke, a Ventura County Fire Department spokesman.

For Californians, such a large fire nearly a month before the official kick-off of the wildfire season is ominous, especially as the National Interagency Fire Service on May 1 predicted a wildfire season of above-normal intensity in both southern and northern California.

Dry conditions abound, making fires easier to ignite, but drought has also stunted undergrowth, limiting potential fire fuel, the fire service reported.

As it stands, even an active fire season would struggle to compete with that of 2012, which nationally burned more than 9 million acres, much of it in Colorado, and of 2011, which saw record wildfires sweep across drought-ravaged Texas, destroying hundreds of homes and burning at least 4 million acres in the Lone Star State alone.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/nWaHkZMb1Wo/California-wildfire-1-900-on-the-lines-as-firefighters-labor-to-limit-damage-video

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Friday, May 3, 2013

Chael Sonnen not retiring, eyes Wanderlei Silva

Chael Sonnen's loss to Jon Jones at UFC 159 put his career in question. At 36 years old, and with title losses in two different divisions, would Sonnen consider retiring? He answered that question on Fuel's "UFC Tonight," and that answer is no.

"I have a lot of goals I want to achieve still, and retirement won't help me get that done," Sonnen said.

He said the weight class is up for debate, though he liked the switch to light heavyweight after years as a middleweight. He would also be happy to fight at a catchweight, like Rich Franklin did for a few fights when moving up in weight. But there's no question about who he wants to fight.

"I'm not going anywhere until me and Wanderlei [Silva] straighten this thing out once and for all,"

Like Sonnen, Silva has moved between middleweight, light heavyweight and catchweights somewhere between. He is also 36, but the sensible match-up isn't why Sonnen is interested in this bout. Sonnen has a problem with this video from 2010:

Here is how Sonnen viewed this video.

"Wanderlei pulled a really dirtbag move on me one time. We're in a van, he mutters something at me, I can't understand what he's saying. He then puts it on YouTube with subtitles because he knows I can't understand him. He puts in these subtitles and I don't know if it's what he's said or not. Essentially, he tells me off, and it looks as though I'm conceding to him. That doesn't fly. If he calls you out, whether it's in a van or not, if you're a fighter, you must respond. I'm ready to respond."

Silva responded by tweeting this:

And then sharing the above video and saying, "Real men talk face to face."

Is this a fight you want to see, Cagereaders? Speak up on Facebook or Twitter.

Other popular content on Yahoo! Sports:
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Source: http://sports.yahoo.com/blogs/mma-cagewriter/chael-sonnen-not-retiring-eyes-wanderlei-silva-182102684.html

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With Record Bond Sale, Apple No Longer 'Thinks ... - Yahoo! Finance

For years the most exceptional of corporate brand names, Apple Inc. (AAPL) is now the quintessential company of the current bull market, relying on the kindness of the bond market to fund an aggressive stock buyback. This maneuver is perfectly in sync with today?s financial-engineering fashion.

A year ago Apple stood astride the financial markets, attaining the highest market value ever as it topped $600 billion. The iJuggernaut?s fabulous profitability, stupendous share-price gains and cult-inspiring products nearly consumed all the capitalist oxygen in a world of muted economic growth, range-trapped stock indexes and plodding technological advances.

More than 90% of brokerage analysts were recommending the stock, it was the most heavily owned name by hedge funds and, at its $702 peak in September 2012, was up 70% for 2012 versus less than 15% for the other 499 stocks in the Standard & Poor?s 500 combined.

A well-known comeuppance

Then came the well-known comeuppance, with stiffer competition in mobile phones, disenchantment with Apple?s new-product slate and an inefficient balance sheet draining growth expectations from Apple shares, which have lost more than 35% of their value in seven months.

In response, Apple CEO Tim Cook and his board have acceded to the pleas of some on Wall Street to liberate some of the value of its huge but massively unproductive $140 billion in idle cash.

A regular dividend payer since a year ago, currently at an increased $12.20-per-share annual rate, Apple is now completing the largest corporate debt offering in history, tapping the pliant capital markets for $17 billion in debt at vanishingly low interest rates.

The cash raised will go toward Apple?s planned $60 billion share buyback over the next couple of years, which would fund the repurchase of 15% of the company from the public at the current stock price. Apple is tapping the debt market rather than repatriating cash it holds overseas, so as not to incur U.S. taxes.

A dominant trend

In this way, Apple has become the largest representative of a dominant trend in the corporate world. Large non-financial companies emerged from the economic crisis in better financial shape, with more cash and borrowing capacity than they needed for fresh capital investments. They have turned share buybacks into a core principle of their ?shareholder value? efforts.

Total share buybacks by S&P 500 companies have approached $100 billion in each of the past three quarters, surpassed only by the excessive (and, in retrospect, ill-advised) buyback orgy of the third quarter of 2007, as the stock indexes reached their prior pre-meltdown peak.

Over the past four quarters, big companies used nearly 80% of their free cash flow to bid for their own stock. Meantime, companies have been supplementing their cash flows with ultra-cheap debt for corporate purposes, including buybacks. In the first quarter, companies sold $365 billion in new debt, says industry trade group SIFMA ? on pace to match last year?s record total near $1.4 trillion.

The buyback binge has been an important, though probably under-appreciated, element of the stock market?s climb to new all-time highs early this year. Helped by the super-cheap cash sluicing through the capital markets, companies facing challenges boosting sales or cutting costs further are, in effect, taking themselves private in increments, thereby goosing per-share earnings by reducing shares in circulation.

A plus for stock performance

On a company-specific level, this activity has made stock performance look a lot better than the gain in overall corporate value. The stock price of AT&T Inc. (T), for instance, gained 17.5% from the end of first quarter 2012 through March 31 of this year. But because the company bought back nearly 7% of its share count over that span, AT&T?s market value rose just 9.3% over the same period.

So far this year and over the past 12 months, the TrimTabs Float Shrink exchange-traded fund (TTFS) ? which owns shares of companies actively reducing their shares outstanding ? has handily outperformed the broad market, proof that the market is, for now, rewarding such activity.

In Apple?s case, this sort of financial engineering makes sense on paper, largely because its cash hoard ? growing fatter every day thanks to heavy cash flows ? is essentially too big for any company to make use of intelligently through capital spending or acquisitions. The market would never fully ?pay? for the cash through its market valuation, so kicking some back to investors with the help of painless borrowing is logical.

At some point, however, companies will prove to have paid too much for overvalued shares, and such paper shuffling won?t indefinitely obscure the reality that many companies don?t have enough organic growth or intrinsic value in their shares to satisfy investors.

Source: http://finance.yahoo.com/blogs/breakout/record-bond-sale-apple-no-longer-thinks-different-150047378.html

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